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Treatment of diabetic peripheral neuropathy with engineered mesenchymal stromal cell-derived exosomes enriched with microRNA-146a provide amplified therapeutic efficacy

Diabetic peripheral neuropathy (DPN) is one of the most prevalent chronic complications of diabetes mellitus with no effective treatment. We recently demonstrated that mesenchymal stromal cell (MSC)-derived exosomes (exo-naïve) alleviate neurovascular dysfunction and improve functional recovery. Mic...

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Vydáno v:Exp Neurol
Hlavní autoři: Fan, Baoyan, Chopp, Michael, Zhang, Zheng Gang, Liu, Xian Shuang
Médium: Artigo
Jazyk:Inglês
Vydáno: 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8169562/
https://ncbi.nlm.nih.gov/pubmed/33727097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2021.113694
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