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Treatment of diabetic peripheral neuropathy with engineered mesenchymal stromal cell-derived exosomes enriched with microRNA-146a provide amplified therapeutic efficacy

Diabetic peripheral neuropathy (DPN) is one of the most prevalent chronic complications of diabetes mellitus with no effective treatment. We recently demonstrated that mesenchymal stromal cell (MSC)-derived exosomes (exo-naïve) alleviate neurovascular dysfunction and improve functional recovery. Mic...

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Bibliographic Details
Published in:Exp Neurol
Main Authors: Fan, Baoyan, Chopp, Michael, Zhang, Zheng Gang, Liu, Xian Shuang
Format: Artigo
Language:Inglês
Published: 2021
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8169562/
https://ncbi.nlm.nih.gov/pubmed/33727097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2021.113694
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