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Exosome‐derived miR‐210 involved in resistance to osimertinib and epithelial–mesenchymal transition in EGFR mutant non‐small cell lung cancer cells

BACKGROUND: Osimertinib is a third‐generation epidermal growth factor receptor‐tyrosine kinase inhibitor (EGFR‐TKI) approved for the treatment of patients with EGFR‐mutant non‐small cell lung cancer (NSCLC). However, the mechanisms of acquired drug resistance to osimertinib have not as yet been clar...

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Detalhes bibliográficos
Publicado no:Thorac Cancer
Main Authors: Hisakane, Kakeru, Seike, Masahiro, Sugano, Teppei, Yoshikawa, Akiko, Matsuda, Kuniko, Takano, Natsuki, Takahashi, Satoshi, Noro, Rintaro, Gemma, Akihiko
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons Australia, Ltd 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8169289/
https://ncbi.nlm.nih.gov/pubmed/33939301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/1759-7714.13943
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