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Exosome‐derived miR‐210 involved in resistance to osimertinib and epithelial–mesenchymal transition in EGFR mutant non‐small cell lung cancer cells

BACKGROUND: Osimertinib is a third‐generation epidermal growth factor receptor‐tyrosine kinase inhibitor (EGFR‐TKI) approved for the treatment of patients with EGFR‐mutant non‐small cell lung cancer (NSCLC). However, the mechanisms of acquired drug resistance to osimertinib have not as yet been clar...

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Publicat a:Thorac Cancer
Autors principals: Hisakane, Kakeru, Seike, Masahiro, Sugano, Teppei, Yoshikawa, Akiko, Matsuda, Kuniko, Takano, Natsuki, Takahashi, Satoshi, Noro, Rintaro, Gemma, Akihiko
Format: Artigo
Idioma:Inglês
Publicat: John Wiley & Sons Australia, Ltd 2021
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8169289/
https://ncbi.nlm.nih.gov/pubmed/33939301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/1759-7714.13943
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