Bundle-specific associations between white matter microstructure and Aβ and tau pathology in preclinical Alzheimer’s disease

Beta-amyloid (Aβ) and tau proteins, the pathological hallmarks of Alzheimer’s disease (AD), are believed to spread through connected regions of the brain. Combining diffusion imaging and positron emission tomography, we investigated associations between white matter microstructure specifically in bu...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Pichet Binette, Alexa, Theaud, Guillaume, Rheault, François, Roy, Maggie, Collins, D Louis, Levin, Johannes, Mori, Hiroshi, Lee, Jae Hong, Farlow, Martin Rhys, Schofield, Peter, Chhatwal, Jasmeer P, Masters, Colin L, Benzinger, Tammie, Morris, John, Bateman, Randall, Breitner, John CS, Poirier, Judes, Gonneaud, Julie, Descoteaux, Maxime, Villeneuve, Sylvia
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2021
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8169107/
https://ncbi.nlm.nih.gov/pubmed/33983116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.62929
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