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Characterization of Alzheimer Disease Biomarker Discrepancies Using Cerebrospinal Fluid Phosphorylated Tau and AV1451 Positron Emission Tomography

IMPORTANCE: Fluid and imaging biomarkers of Alzheimer disease (AD) are often used interchangeably, but some biomarkers may reveal earlier stages of disease. OBJECTIVE: To characterize individuals with tau abnormality indicated by cerebrospinal fluid (CSF) assay or positron emission tomography (PET)....

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Publicado en:JAMA Neurol
Main Authors: Meyer, Pierre-François, Pichet Binette, Alexa, Gonneaud, Julie, Breitner, John C. S., Villeneuve, Sylvia
Formato: Artigo
Idioma:Inglês
Publicado: American Medical Association 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6990861/
https://ncbi.nlm.nih.gov/pubmed/31961372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaneurol.2019.4749
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