Bundle-specific associations between white matter microstructure and Aβ and tau pathology in preclinical Alzheimer’s disease

Beta-amyloid (Aβ) and tau proteins, the pathological hallmarks of Alzheimer’s disease (AD), are believed to spread through connected regions of the brain. Combining diffusion imaging and positron emission tomography, we investigated associations between white matter microstructure specifically in bu...

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Veröffentlicht in:eLife
Hauptverfasser: Pichet Binette, Alexa, Theaud, Guillaume, Rheault, François, Roy, Maggie, Collins, D Louis, Levin, Johannes, Mori, Hiroshi, Lee, Jae Hong, Farlow, Martin Rhys, Schofield, Peter, Chhatwal, Jasmeer P, Masters, Colin L, Benzinger, Tammie, Morris, John, Bateman, Randall, Breitner, John CS, Poirier, Judes, Gonneaud, Julie, Descoteaux, Maxime, Villeneuve, Sylvia
Format: Artigo
Sprache:Inglês
Veröffentlicht: eLife Sciences Publications, Ltd 2021
Schlagworte:
Neuroscience
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8169107/
https://ncbi.nlm.nih.gov/pubmed/33983116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.62929
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