Nestin(+)/CD31(+) cells in the hypoxic perivascular niche regulate glioblastoma chemoresistance by upregulating JAG1 and DLL4

BACKGROUND: Failure of glioblastoma (GBM) therapy is often ascribed to different types of glioblastoma stem-like cell (GSLC) niche; in particular, a hypoxic perivascular niche (HPVN) is involved in GBM progression. However, the cells responsible for HPVNs remain unclear. METHODS: Immunostaining was...

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Bibliographic Details
Published in:Neuro Oncol
Main Authors: Zheng, Zong-Qing, Chen, Jin-Tao, Zheng, Ming-Cheng, Yang, Li-Juan, Wang, Jun-Ming, Liu, Quan-Li, Chen, Lu-Fei, Ye, Zu-Cheng, Lin, Jin-Ming, Lin, Zhi-Xiong
Format: Artigo
Language:Inglês
Published: Oxford University Press 2020
Subjects:
Basic and Translational Investigations
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8168822/
https://ncbi.nlm.nih.gov/pubmed/33249476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa265
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