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TMIC-46. TUNING OF HYPOXIC AND PSEUDO-HYPOXIC GLIOMA PHENOTYPES IN PERIVASCULAR AND PERINECROTIC NICHES

Stem-like glioma cells have been proposed to reside in hypoxic and/or perivascular tumor niches. Such cells display an amplified cellular response to hypoxia, and appear to have a pseudo-hypoxic phenotype both at normoxia in vitro, and in a well-oxygenated perivascular niche in vivo. Hypoxia-inducib...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Johansson, Elinn, Grassi, Elisa, Pantazopoulou, Vasiliki, Tong, Bei, Lindgren, David, Berg, Tracy, Axelson, Håkan, Pietras, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5692874/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.1034
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