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Tracking pre-mRNA maturation across subcellular compartments identifies developmental gene regulation through intron retention and nuclear anchoring

Steps of mRNA maturation are important gene regulatory events that occur in distinct cellular locations. However, transcriptomic analyses often lose information on the subcellular distribution of processed and unprocessed transcripts. We generated extensive RNA-seq data sets to track mRNA maturation...

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Detalles Bibliográficos
Publicado en:Genome Res
Main Authors: Yeom, Kyu-Hyeon, Pan, Zhicheng, Lin, Chia-Ho, Lim, Han Young, Xiao, Wen, Xing, Yi, Black, Douglas L.
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8168582/
https://ncbi.nlm.nih.gov/pubmed/33832989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.273904.120
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