Tracking pre-mRNA maturation across subcellular compartments identifies developmental gene regulation through intron retention and nuclear anchoring

Steps of mRNA maturation are important gene regulatory events that occur in distinct cellular locations. However, transcriptomic analyses often lose information on the subcellular distribution of processed and unprocessed transcripts. We generated extensive RNA-seq data sets to track mRNA maturation...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Genome Res
Prif Awduron: Yeom, Kyu-Hyeon, Pan, Zhicheng, Lin, Chia-Ho, Lim, Han Young, Xiao, Wen, Xing, Yi, Black, Douglas L.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Cold Spring Harbor Laboratory Press 2021
Pynciau:
Resource
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC8168582/
https://ncbi.nlm.nih.gov/pubmed/33832989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.273904.120
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