Tracking pre-mRNA maturation across subcellular compartments identifies developmental gene regulation through intron retention and nuclear anchoring

Steps of mRNA maturation are important gene regulatory events that occur in distinct cellular locations. However, transcriptomic analyses often lose information on the subcellular distribution of processed and unprocessed transcripts. We generated extensive RNA-seq data sets to track mRNA maturation...

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Foilsithe in:Genome Res
Main Authors: Yeom, Kyu-Hyeon, Pan, Zhicheng, Lin, Chia-Ho, Lim, Han Young, Xiao, Wen, Xing, Yi, Black, Douglas L.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Cold Spring Harbor Laboratory Press 2021
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Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8168582/
https://ncbi.nlm.nih.gov/pubmed/33832989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.273904.120
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