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Protein neddylation as a therapeutic target in pulmonary and extrapulmonary small cell carcinomas
Small cell lung carcinoma (SCLC) is among the most lethal of all solid tumor malignancies. In an effort to identify novel therapeutic approaches for this recalcitrant cancer type, we applied genome-scale CRISPR/Cas9 inactivation screens to cell lines that we derived from a murine model of SCLC. SCLC...
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| 發表在: | Genes Dev |
|---|---|
| Main Authors: | , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Cold Spring Harbor Laboratory Press
2021
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8168556/ https://ncbi.nlm.nih.gov/pubmed/34016692 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.348316.121 |
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