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PTEN is a Potent Suppressor of Small Cell Lung Cancer

Small cell lung carcinoma (SCLC) is a highly metastatic tumor type with neuroendocrine features and a dismal prognosis. PTEN mutations and PIK3CA activating mutations have been reported in SCLC but the functional relevance of this pathway is unknown. The PTEN/PIK3CA pathway was interrogated using an...

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Detalhes bibliográficos
Main Authors: Cui, Min, Augert, Arnaud, Rongione, Michael, Conkrite, Karina, Parazzoli, Susan, Nikitin, Alexander Yu., Ingolia, Nicholas, MacPherson, David
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4020961/
https://ncbi.nlm.nih.gov/pubmed/24482365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-13-0554
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