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Small Cell Lung Cancer Exhibits Frequent Inactivating Mutations in the Histone Methyltransferase KMT2D/MLL2: CALGB 151111 (Alliance)

INTRODUCTION: SCLC is a lethal neuroendocrine tumor type that is highly prone to metastasis. There is an urgency to understand the mutated genes that promote SCLC, as there are no approved targeted therapies yet available. SCLC is rarely resected, limiting the number of samples available for genomic...

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Detalhes bibliográficos
Publicado no:J Thorac Oncol
Main Authors: Augert, Arnaud, Zhang, Qing, Bates, Breanna, Cui, Min, Wang, Xiaofei, Wildey, Gary, Dowlati, Afshin, MacPherson, David
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5669801/
https://ncbi.nlm.nih.gov/pubmed/28007623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtho.2016.12.011
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