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Hijacked in cancer: the MLL/KMT2 family of methyltransferases
Lysine methyltransferase 2 family (KMT2) proteins methylate lysine 4 on the histone H3 tail at important regulatory regions in the genome and thus impart critical functions through modulating chromatin structures and DNA accessibility. While the human KMT2 family was initially named the mixed lineag...
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| Publicado no: | Nat Rev Cancer |
|---|---|
| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4493861/ https://ncbi.nlm.nih.gov/pubmed/25998713 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrc3929 |
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