The Chromatin Accessibility Landscape of Peripheral Blood Mononuclear Cells in Patients With Systemic Lupus Erythematosus at Single-Cell Resolution

OBJECTIVE: Systemic lupus erythematosus (SLE) is a complex autoimmune disease, and various immune cells are involved in the initiation, progression, and regulation of SLE. Our goal was to reveal the chromatin accessibility landscape of peripheral blood mononuclear cells (PBMCs) in SLE patients at si...

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Veröffentlicht in:Front Immunol
Hauptverfasser: Yu, Haiyan, Hong, Xiaoping, Wu, Hongwei, Zheng, Fengping, Zeng, Zhipeng, Dai, Weier, Yin, Lianghong, Liu, Dongzhou, Tang, Donge, Dai, Yong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2021
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8168536/
https://ncbi.nlm.nih.gov/pubmed/34084162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.641886
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