Gene-regulatory network analysis of ankylosing spondylitis with a single-cell chromatin accessible assay

A detailed understanding of the gene-regulatory network in ankylosing spondylitis (AS) is vital for elucidating the mechanisms of AS pathogenesis. Assaying transposase-accessible chromatin in single cell sequencing (scATAC-seq) is a suitable method for revealing such networks. Thus, scATAC-seq was a...

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Vydáno v:Sci Rep
Hlavní autoři: Yu, Haiyan, Wu, Hongwei, Zheng, Fengping, Zhu, Chengxin, Yin, Lianghong, Dai, Weier, Liu, Dongzhou, Tang, Donge, Hong, Xiaoping, Dai, Yong
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7655814/
https://ncbi.nlm.nih.gov/pubmed/33173081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-76574-5
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