Single-cell chromatin accessibility landscape of human umbilical cord blood in trisomy 18 syndrome

BACKGROUND: Trisomy 18 syndrome (Edwards syndrome, ES) is a type of aneuploidy caused by the presence of an extra chromosome 18. Aneuploidy is the leading cause of early pregnancy loss, intellectual disability, and multiple congenital anomalies. The research of trisomy 18 is progressing slowly, and...

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Bibliographic Details
Published in:	Hum Genomics
Main Authors:	Qiu, Xiaofen, Yu, Haiyan, Wu, Hongwei, Hu, Zhiyang, Zhou, Jun, Lin, Hua, Xue, Wen, Cai, Wanxia, Chen, Jiejing, Yan, Qiang, Dai, Weier, Yang, Ming, Tang, Donge, Dai, Yong
Format:	Artigo
Language:	Inglês
Published:	BioMed Central 2021
Subjects:	Primary Research
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC8246660/ https://ncbi.nlm.nih.gov/pubmed/34193281 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40246-021-00338-z
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Single-cell chromatin accessibility landscape of human umbilical cord blood in trisomy 18 syndrome

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