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HGG-26. SINGLE-CELL RNA-SEQ OF PEDIATRIC HIGH-GRADE GLIOMAS IDENTIFIES COMMON ONCOGENIC PROCESSES AMONG DISTINCT TUMOR HISTOLOGIES

BACKGROUND: Pediatric high-grade glioma (PHGG) is a deadly childhood brain tumor that responds poorly to treatment. PHGG comprises two major subtypes: cortical tumors with wild-type H3K27 and diffuse midline gliomas (DMG) that occur in the midline and have characteristic H3K27M mutations. Cortical P...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: DeSisto, John, Donson, Andrew, Fu, Rui, Sanford, Bridget, Riemondy, Kent, Green, Adam
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8168164/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noab090.090
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