HGG-57. WHOLE-GENOME SEQUENCING, METHYLATION ANALYSIS, AND SINGLE-CELL RNA-SEQ DEFINE UNIQUE CHARACTERISTICS OF PEDIATRIC TREATMENT-INDUCED HIGH-GRADE GLIOMA AND SUGGEST ONCOGENIC MECHANISMS

BACKGROUND: Pediatric treatment-induced high-grade glioma (TIHGG) is among the most severe late effects observed in childhood cancer survivors and is uniformly fatal. We previously showed that TIHGG are divergent from de novo pediatric high-grade glioma (pHGG) and cluster into two gene expression su...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Neuro Oncol
Main Authors: Lucas, John, DeSisto, John, Xu, Ke, Donson, Andrew, Lin, Tong, Sanford, Bridget, Wu, Gang, Tran, Quynh, Hedges, Dale, Hsu, Chih-Yang, Armstrong, Gregory, Arnold, Michael, Bhatia, Smita, Flannery, Patrick, Lemma, Rakeb, Hardie, Lakotah, Schuller, Ulrich, Hoffman, Lindsey, Dorris, Kathleen, Levy, Jean, Hankinson, Todd, Handler, Michael, Liu, Arthur, Foreman, Nicholas, Vibhakar, Rajeev, Jones, Kenneth, Allen, Sariah, Zhang, Jinghui, Baker, Suzanne, Merchant, Thomas, Orr, Brent, Green, Adam
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2020
Assuntos:
High Grade Glioma
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7715357/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa222.336
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares