HGG-57. WHOLE-GENOME SEQUENCING, METHYLATION ANALYSIS, AND SINGLE-CELL RNA-SEQ DEFINE UNIQUE CHARACTERISTICS OF PEDIATRIC TREATMENT-INDUCED HIGH-GRADE GLIOMA AND SUGGEST ONCOGENIC MECHANISMS

BACKGROUND: Pediatric treatment-induced high-grade glioma (TIHGG) is among the most severe late effects observed in childhood cancer survivors and is uniformly fatal. We previously showed that TIHGG are divergent from de novo pediatric high-grade glioma (pHGG) and cluster into two gene expression su...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Neuro Oncol
मुख्य लेखकों: Lucas, John, DeSisto, John, Xu, Ke, Donson, Andrew, Lin, Tong, Sanford, Bridget, Wu, Gang, Tran, Quynh, Hedges, Dale, Hsu, Chih-Yang, Armstrong, Gregory, Arnold, Michael, Bhatia, Smita, Flannery, Patrick, Lemma, Rakeb, Hardie, Lakotah, Schuller, Ulrich, Hoffman, Lindsey, Dorris, Kathleen, Levy, Jean, Hankinson, Todd, Handler, Michael, Liu, Arthur, Foreman, Nicholas, Vibhakar, Rajeev, Jones, Kenneth, Allen, Sariah, Zhang, Jinghui, Baker, Suzanne, Merchant, Thomas, Orr, Brent, Green, Adam
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Oxford University Press 2020
विषय:
High Grade Glioma
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC7715357/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa222.336
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