Mutation of a conserved glutamine residue does not abolish desensitization of acid-sensing ion channel 1

Desensitization is a common feature of ligand-gated ion channels, although the molecular cause varies widely between channel types. Mutations that greatly reduce or nearly abolish desensitization have been described for many ligand-gated ion channels, including glutamate, GABA, glycine, and nicotini...

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Bibliografiska uppgifter
I publikationen:J Gen Physiol
Huvudupphovsmän: Rook, Matthew L., Miaro, Megan, Couch, Tyler, Kneisley, Dana L., Musgaard, Maria, MacLean, David M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Rockefeller University Press 2021
Ämnen:
Communication
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC8167889/
https://ncbi.nlm.nih.gov/pubmed/34061161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.202012855
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