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The Thumb Domain Mediates Acid-sensing Ion Channel Desensitization

Acid-sensing ion channels (ASICs) are cation-selective proton-gated channels expressed in neurons that participate in diverse physiological processes, including nociception, synaptic plasticity, learning, and memory. ASIC subunits contain intracellular N and C termini, two transmembrane domains that...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Krauson, Aram J., Carattino, Marcelo D.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4900284/
https://ncbi.nlm.nih.gov/pubmed/27015804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.702316
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