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Mutation of a conserved glutamine residue does not abolish desensitization of acid-sensing ion channel 1
Desensitization is a common feature of ligand-gated ion channels, although the molecular cause varies widely between channel types. Mutations that greatly reduce or nearly abolish desensitization have been described for many ligand-gated ion channels, including glutamate, GABA, glycine, and nicotini...
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| Veröffentlicht in: | J Gen Physiol |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Rockefeller University Press
2021
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8167889/ https://ncbi.nlm.nih.gov/pubmed/34061161 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.202012855 |
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