Minnelide, a prodrug, inhibits cervical cancer growth by blocking HPV-induced changes in p53 and pRb

HPV-induced cervical cancer is one of the prevalent gynecological cancers world-wide. In the present study, we determined the efficacy of Minnelide, a prodrug which is converted to its active form (Triptolide) in vivo against cervical cancer cells. Our studies show that Triptolide inhibited HPV-16 a...

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Detalhes bibliográficos
Publicado no:Am J Cancer Res
Main Authors: Ramakrishnan, Vivek, de Haydu, Christopher, Wilkinson, Peter, Hooda, Urvashi, Giri, Bhuwan, Oleas, Janneth M, Rive, Veronica, Roy, Sabita, Dudeja, Vikas, Slomovitch, Brian, Saluja, Ashok, Ramakrishnan, Sundaram
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2021
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8167699/
https://ncbi.nlm.nih.gov/pubmed/34094678
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