Improved cardiac-specific delivery of RAGE siRNA within small extracellular vesicles engineered to express intense cardiac targeting peptide attenuates myocarditis

Small extracellular vesicles (sEVs) are nanometer-sized membranous vesicles secreted by cells, with important roles in physiological and pathological processes. Recent research has established the application of sEVs as therapeutic vehicles in various conditions, including heart disease. However, th...

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Dades bibliogràfiques
Publicat a:Mol Ther Nucleic Acids
Autors principals: Kim, Hyoeun, Mun, Dasom, Kang, Ji-Young, Lee, Seung-Hyun, Yun, Nuri, Joung, Boyoung
Format: Artigo
Idioma:Inglês
Publicat: American Society of Gene & Cell Therapy 2021
Matèries:
Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8167198/
https://ncbi.nlm.nih.gov/pubmed/34141457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2021.04.018
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