Improved cardiac-specific delivery of RAGE siRNA within small extracellular vesicles engineered to express intense cardiac targeting peptide attenuates myocarditis

Small extracellular vesicles (sEVs) are nanometer-sized membranous vesicles secreted by cells, with important roles in physiological and pathological processes. Recent research has established the application of sEVs as therapeutic vehicles in various conditions, including heart disease. However, th...

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Spremljeno u:
Bibliografski detalji
Izdano u:Mol Ther Nucleic Acids
Glavni autori: Kim, Hyoeun, Mun, Dasom, Kang, Ji-Young, Lee, Seung-Hyun, Yun, Nuri, Joung, Boyoung
Format: Artigo
Jezik:Inglês
Izdano: American Society of Gene & Cell Therapy 2021
Teme:
Original Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8167198/
https://ncbi.nlm.nih.gov/pubmed/34141457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2021.04.018
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