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Improved cardiac-specific delivery of RAGE siRNA within small extracellular vesicles engineered to express intense cardiac targeting peptide attenuates myocarditis

Small extracellular vesicles (sEVs) are nanometer-sized membranous vesicles secreted by cells, with important roles in physiological and pathological processes. Recent research has established the application of sEVs as therapeutic vehicles in various conditions, including heart disease. However, th...

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Detalhes bibliográficos
Publicado no:Mol Ther Nucleic Acids
Main Authors: Kim, Hyoeun, Mun, Dasom, Kang, Ji-Young, Lee, Seung-Hyun, Yun, Nuri, Joung, Boyoung
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8167198/
https://ncbi.nlm.nih.gov/pubmed/34141457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2021.04.018
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