WDR62 is required for centriole duplication in spermatogenesis and manchette removal in spermiogenesis

WDR62 is a scaffold protein involved in centriole duplication and spindle assembly during mitosis. Mutations in WDR62 can cause primary microcephaly and premature ovarian insufficiency. We have generated a genetrap mouse model deficient in WDR62 and characterised the developmental effects of WDR62 d...

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Détails bibliographiques
Publié dans:Commun Biol
Auteurs principaux: Ho, Uda Y., Feng, Chun-Wei Allen, Yeap, Yvonne Y., Bain, Amanda L., Wei, Zhe, Shohayeb, Belal, Reichelt, Melissa E., Homer, Hayden, Khanna, Kum Kum, Bowles, Josephine, Ng, Dominic C. H.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2021
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8167107/
https://ncbi.nlm.nih.gov/pubmed/34059773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-021-02171-5
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