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The Spindle-Associated Microcephaly Protein, WDR62, Is Required for Neurogenesis and Development of the Hippocampus

Primary microcephaly genes (MCPH) are required for the embryonic expansion of the mammalian cerebral cortex. However, MCPH mutations may spare growth in other regions of the developing forebrain which reinforces context-dependent functions for distinct MCPH genes in neurodevelopment. Mutations in th...

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Détails bibliographiques
Publié dans:Front Cell Dev Biol
Auteurs principaux: Shohayeb, Belal, Ho, Uda Y., Hassan, Halah, Piper, Michael, Ng, Dominic C. H.
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7517699/
https://ncbi.nlm.nih.gov/pubmed/33042990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.549353
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