Gender biased neuroprotective effect of Transferrin Receptor 2 deletion in multiple models of Parkinson’s disease

Alterations in the metabolism of iron and its accumulation in the substantia nigra pars compacta accompany the pathogenesis of Parkinson’s disease (PD). Changes in iron homeostasis also occur during aging, which constitutes a PD major risk factor. As such, mitigation of iron overload via chelation s...

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Publicado en:Cell Death Differ
Main Authors: Milanese, Chiara, Gabriels, Sylvia, Barnhoorn, Sander, Cerri, Silvia, Ulusoy, Ayse, Gornati, S. V., Wallace, Daniel F., Blandini, Fabio, Di Monte, Donato A., Subramaniam, V. Nathan, Mastroberardino, Pier G.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2020
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8166951/
https://ncbi.nlm.nih.gov/pubmed/33323945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-020-00698-4
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