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Loss of ferroportin induces memory impairment by promoting ferroptosis in Alzheimer’s disease

Iron homeostasis disturbance has been implicated in Alzheimer’s disease (AD), and excess iron exacerbates oxidative damage and cognitive defects. Ferroptosis is a nonapoptotic form of cell death dependent upon intracellular iron. However, the involvement of ferroptosis in the pathogenesis of AD rema...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Cell Death Differ
Hauptverfasser: Bao, Wen-Dai, Pang, Pei, Zhou, Xiao-Ting, Hu, Fan, Xiong, Wan, Chen, Kai, Wang, Jing, Wang, Fudi, Xie, Dong, Hu, Ya-Zhuo, Han, Zhi-Tao, Zhang, Hong-Hong, Wang, Wang-Xia, Nelson, Peter T., Chen, Jian-Guo, Lu, Youming, Man, Heng-Ye, Liu, Dan, Zhu, Ling-Qiang
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8166828/
https://ncbi.nlm.nih.gov/pubmed/33398092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-020-00685-9
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