2′-O methylation of RNA cap in SARS-CoV-2 captured by serial crystallography

The genome of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) coronavirus has a capping modification at the 5′-untranslated region (UTR) to prevent its degradation by host nucleases. These modifications are performed by the Nsp10/14 and Nsp10/16 heterodimers using S-adenosylmethioni...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Wilamowski, Mateusz, Sherrell, Darren A., Minasov, George, Kim, Youngchang, Shuvalova, Ludmilla, Lavens, Alex, Chard, Ryan, Maltseva, Natalia, Jedrzejczak, Robert, Rosas-Lemus, Monica, Saint, Nickolaus, Foster, Ian T., Michalska, Karolina, Satchell, Karla J. F., Joachimiak, Andrzej
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2021
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8166198/
https://ncbi.nlm.nih.gov/pubmed/33972410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2100170118
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