Wordt geladen...

High-resolution structures of the SARS-CoV-2 2’-O-methyltransferase reveal strategies for structure-based inhibitor design

There are currently no antiviral therapies specific for SARS-CoV-2, the virus responsible for the global pandemic disease COVID-19. To facilitate structure-based drug design, we conducted an X-ray crystallographic study of the SARS-CoV-2 nsp16-nsp10 2′-O-methyltransferase complex, which methylates C...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:Sci Signal
Hoofdauteurs: Rosas-Lemus, Monica, Minasov, George, Shuvalova, Ludmilla, Inniss, Nicole, Kiryukhina, Olga, Brunzelle, Joseph, Satchell, Karla J. F.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2020
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8028745/
https://ncbi.nlm.nih.gov/pubmed/32994211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.abe1202
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!