Cerebrospinal Fluid Sulfonylurea Receptor-1 is Associated with Intracranial Pressure and Outcome after Pediatric TBI: An Exploratory Analysis of the Cool Kids Trial

Sulfonylurea receptor-1 (SUR1) is recognized increasingly as a key contributor to cerebral edema, hemorrhage progression, and possibly neuronal death in multiple forms of acute brain injury. SUR1 inhibition may be protective and is actively undergoing evaluation in Phase-2/3 trials of traumatic brai...

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Détails bibliographiques
Publié dans:J Neurotrauma
Auteurs principaux: Zusman, Benjamin E., Kochanek, Patrick M., Bell, Michael J., Adelson, P. David, Wisniewski, Stephen R., Au, Alicia K., Clark, Robert S.B., Bayır, Hülya, Janesko-Feldman, Keri, Jha, Ruchira M.
Format: Artigo
Langue:Inglês
Publié: Mary Ann Liebert, Inc., publishers 2021
Sujets:
Original Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8165477/
https://ncbi.nlm.nih.gov/pubmed/33430695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/neu.2020.7501
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