Cerebrospinal Fluid Levels of High-Mobility Group Box 1 and Cytochrome C Predict Outcome after Pediatric Traumatic Brain Injury

High-mobility group box 1 (HMGB1) is a ubiquitous nuclear protein that is passively released from damaged and necrotic cells, and actively released from immune cells. In contrast, cytochrome c is released from mitochondria in apoptotic cells, and is considered a reliable biomarker of apoptosis. Thus...

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Main Authors: Au, Alicia K., Aneja, Rajesh K., Bell, Michael J., Bayir, Hülya, Feldman, Keri, Adelson, P. David, Fink, Ericka L., Kochanek, Patrick M., Clark, Robert S.B.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2012
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3408241/
https://ncbi.nlm.nih.gov/pubmed/22540160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/neu.2011.2171
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