Non-canonical NRF2 activation promotes a pro-diabetic shift in hepatic glucose metabolism

OBJECTIVE: NRF2, a transcription factor that regulates cellular redox and metabolic homeostasis, plays a dual role in human disease. While it is well known that canonical intermittent NRF2 activation protects against diabetes-induced tissue damage, little is known regarding the effects of prolonged...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Mol Metab
Main Authors: Liu, Pengfei, Dodson, Matthew, Li, Hui, Schmidlin, Cody J., Shakya, Aryatara, Wei, Yongyi, Garcia, Joe G.N., Chapman, Eli, Kiela, Pawel R., Zhang, Qing-Yu, White, Eileen, Ding, Xinxin, Ooi, Aikseng, Zhang, Donna D.
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2021
Teme:
Brief Communication
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8164084/
https://ncbi.nlm.nih.gov/pubmed/33933676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2021.101243
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