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Modulating NRF2 in disease: Timing is everything

The transcription factor nuclear factor erythroid-2 (NF-E2)-related factor 2 (NRF2) is a central regulator of redox, metabolic, and protein homeostasis that intersects with many other signaling cascades. While the understanding of the complex nature of NRF2 signaling continues to grow, there is only...

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Detalhes bibliográficos
Publicado no:Annu Rev Pharmacol Toxicol
Main Authors: Dodson, Matthew, de la Vega, Montserrat Rojo, Cholanians, Aram B., Schmidlin, Cody J., Chapman, Eli, Zhang, Donna D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6538038/
https://ncbi.nlm.nih.gov/pubmed/30256716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-pharmtox-010818-021856
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