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NRF2-targeted therapeutics: New targets and modes of NRF2 regulation

Pharmacological activation of the transcription factor nuclear factor-erythroid derived 2-like 2 (NRF2), the key regulator of the cellular antioxidant response, has been recognized as a feasible strategy to reduce oxidative/electrophilic stress and prevent carcinogenesis or other chronic illnesses,...

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Bibliographic Details
Published in:Curr Opin Toxicol
Main Authors: Rojo de la Vega, Montserrat, Dodson, Matthew, Chapman, Eli, Zhang, Donna D.
Format: Artigo
Language:Inglês
Published: 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5654570/
https://ncbi.nlm.nih.gov/pubmed/29082352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cotox.2016.10.005
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