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Molecular mechanisms of Nrf2 regulation and how these influence chemical modulation for disease intervention
Nrf2 (nuclear factor erytheroid-derived-2-like 2) transcriptional programmes are activated by a variety of cellular stress conditions to maintain cellular homoeostasis. Under non-stress conditions, Nrf2 is under tight regulation by the ubiquitin proteasome system (UPS). Detailed mechanistic investig...
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Publicado no: | Biochem Soc Trans |
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Main Authors: | , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Portland Press Ltd.
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4613518/ https://ncbi.nlm.nih.gov/pubmed/26551712 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BST20150020 |
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