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FAM129B-dependent activation of NRF2 promotes an invasive phenotype in BRAF mutant melanoma cells

Incidence of melanoma continues to rise in the United States with ~100,000 new cases diagnosed in 2019. While the 5-year survival rate of melanoma is 99% when localized, the rate of survival drops to 22.5% when distant disease is detected. As such, an area of great interest is understanding the mech...

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Detalhes bibliográficos
Publicado no:Mol Carcinog
Main Authors: Schmidlin, Cody J., Tian, Wang, Dodson, Matthew, Chapman, Eli, Zhang, Donna D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8189631/
https://ncbi.nlm.nih.gov/pubmed/33684228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mc.23295
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