Analysis of genes regulated by DUX4 via oxidative stress reveals potential therapeutic targets for treatment of facioscapulohumeral dystrophy

Muscles of patients with facioscapulohumeral dystrophy (FSHD) are characterized by sporadic DUX4 expression and oxidative stress which is at least partially induced by DUX4 protein. Nevertheless, targeting oxidative stress with antioxidants has a limited impact on FSHD patients, and the exact role o...

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Detalhes bibliográficos
Publicado no:Redox Biol
Main Authors: Karpukhina, Anna, Galkin, Ivan, Ma, Yinxing, Dib, Carla, Zinovkin, Roman, Pletjushkina, Olga, Chernyak, Boris, Popova, Ekaterina, Vassetzky, Yegor
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2021
Assuntos:
Short Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8163973/
https://ncbi.nlm.nih.gov/pubmed/34030118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2021.102008
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