Hydroxyurea improves nitric oxide bioavailability in humanized sickle cell mice

Despite advancements in disease management, sickle cell nephropathy, a major contributor to mortality and morbidity in patients, has limited therapeutic options. Previous studies indicate hydroxyurea, a commonly prescribed therapy for sickle cell disease (SCD), can reduce renal injury in SCD but the...

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Détails bibliographiques
Publié dans:Am J Physiol Regul Integr Comp Physiol
Auteurs principaux: Taylor, Crystal M., Kasztan, Malgorzata, Sedaka, Randee, Molina, Patrick A., Dunaway, Luke S., Pollock, Jennifer S., Pollock, David M.
Format: Artigo
Langue:Inglês
Publié: American Physiological Society 2021
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8163606/
https://ncbi.nlm.nih.gov/pubmed/33624556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00205.2020
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