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Hyperfiltration predicts long-term renal outcomes in humanized sickle cell mice

We previously reported that humanized sickle cell (HbSS) mice develop spontaneous nephropathy, a major cause of morbidity and mortality in sickle cell disease (SCD). Because sex-dependent protective mechanisms in SCD have been reported, we examined the course of nephropathy in male and female HbSS m...

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Publicat a:Blood Adv
Autors principals: Kasztan, Malgorzata, Fox, Brandon M., Lebensburger, Jeffrey D., Hyndman, Kelly A., Speed, Joshua S., Pollock, Jennifer S., Pollock, David M.
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6517665/
https://ncbi.nlm.nih.gov/pubmed/31064747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2018028878
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