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Metal-chelating benzothiazole multifunctional compounds for the modulation and (64)Cu PET imaging of Aβ aggregation

While Alzheimer's Disease (AD) is the most common neurodegenerative disease, there is still a dearth of efficient therapeutic and diagnostic agents for this disorder. Reported herein are a series of new multifunctional compounds (MFCs) with appreciable affinity for amyloid aggregates that can b...

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Detalhes bibliográficos
Publicado no:Chem Sci
Main Authors: Huang, Yiran, Cho, Hong-Jun, Bandara, Nilantha, Sun, Liang, Tran, Diana, Rogers, Buck E., Mirica, Liviu M.
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society of Chemistry 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8163150/
https://ncbi.nlm.nih.gov/pubmed/34094152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0sc02641g
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