Transferrin Conjugates of Triazacyclononane-Based Bifunctional NE3TA Chelates for PET Imaging: Synthesis, Cu-64 Radiolabeling, and In vitro and In vivo evaluation

Three different polyaminocarboxylate-based bifunctional NE3TA (7-[2-[carboxymethyl)amino]ethyl]-1,4,7-triazacyclononane-1,4-diacetic acid) chelating agents were synthesized for potential use in copper 64-PET imaging applications. The bifunctional chelates were comparatively evaluated using transferr...

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Detalhes bibliográficos
Publicado no:J Inorg Biochem
Main Authors: Kang, Chi Soo, Wu, Ningjie, Chen, Yunwei, Sun, Xiang, Bandara, Nilantha, Liu, Dijie, Lewis, Michael, Rogers, Buck, Chong, Hyun-Soon
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4679499/
https://ncbi.nlm.nih.gov/pubmed/26583705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jinorgbio.2015.10.012
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