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Mathematical modeling of multiple pathways in colorectal carcinogenesis using dynamical systems with Kronecker structure

Like many other types of cancer, colorectal cancer (CRC) develops through multiple pathways of carcinogenesis. This is also true for colorectal carcinogenesis in Lynch syndrome (LS), the most common inherited CRC syndrome. However, a comprehensive understanding of the distribution of these pathways...

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Detalhes bibliográficos
Publicado no:PLoS Comput Biol
Main Authors: Haupt, Saskia, Zeilmann, Alexander, Ahadova, Aysel, Bläker, Hendrik, von Knebel Doeberitz, Magnus, Kloor, Matthias, Heuveline, Vincent
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8162698/
https://ncbi.nlm.nih.gov/pubmed/34003820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1008970
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