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Transient IL-33 upregulation in neonatal mouse lung promotes acute but not chronic type 2 immune responses induced by allergen later in life

Early life respiratory insults, such as viral infections or hyperoxia, often increase asthma susceptibility later in life. The mechanisms underlying this increased susceptibility are not fully understood. IL-33 has been shown to be critically involved in allergic airway diseases. IL-33 expression in...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Iijima, Koji, Kobayashi, Takao, Matsumoto, Koji, Ohara, Kenzo, Kita, Hirohito, Drake, Li Y.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8162637/
https://ncbi.nlm.nih.gov/pubmed/34048460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0252199
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