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Transient IL-33 upregulation in neonatal mouse lung promotes acute but not chronic type 2 immune responses induced by allergen later in life

Early life respiratory insults, such as viral infections or hyperoxia, often increase asthma susceptibility later in life. The mechanisms underlying this increased susceptibility are not fully understood. IL-33 has been shown to be critically involved in allergic airway diseases. IL-33 expression in...

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Библиографические подробности
Опубликовано в: :PLoS One
Главные авторы: Iijima, Koji, Kobayashi, Takao, Matsumoto, Koji, Ohara, Kenzo, Kita, Hirohito, Drake, Li Y.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2021
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC8162637/
https://ncbi.nlm.nih.gov/pubmed/34048460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0252199
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