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IL-33 dysregulates regulatory T (Treg) cells and impairs established immunological tolerance in the lungs
BACKGROUND: Airway exposure to environmental antigens generally leads to immunological tolerance. A fundamental question remains: why is airway tolerance compromised in patients with allergic airway diseases? Interleukin (IL)-33 promotes innate and adaptive type 2 immunity and may provide the answer...
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| Publicado no: | J Allergy Clin Immunol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5554091/ https://ncbi.nlm.nih.gov/pubmed/28196763 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2017.01.015 |
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