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THE DANGER SIGNAL, EXTRACELLULAR ATP, IS A SENSOR FOR AN AIRBORNE ALLERGEN AND TRIGGERS IL-33 RELEASE AND INNATE TH2-TYPE RESPONSES

The molecular mechanisms underlying the initiation of innate and adaptive proallergic Th2-type responses in the airways are not well understood. IL-33 is a new member of the IL-1 family molecules that is implicated in Th2-type responses. Airway exposure of naïve mice to a common environmental aeroal...

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Detalhes bibliográficos
Main Authors: Kouzaki, Hideaki, Iijima, Koji, Kobayashi, Takao, O’Grady, Scott M., Kita, Hirohito
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3062674/
https://ncbi.nlm.nih.gov/pubmed/21357533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1003020
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