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Cancer cell-selective modulation of mitochondrial respiration and metabolism by potent organogold(iii) dithiocarbamates

Metabolic reprogramming is a key cancer hallmark that has led to the therapeutic targeting of glycolysis. However, agents that target dysfunctional mitochondrial respiration for targeted therapy remains underexplored. We report the synthesis and characterization of ten (10) novel, highly potent orga...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Chem Sci
मुख्य लेखकों: Mertens, Randall T., Parkin, Sean, Awuah, Samuel G.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: The Royal Society of Chemistry 2020
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC8162438/
https://ncbi.nlm.nih.gov/pubmed/34094305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0sc03628e
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