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Iminophosphorane-organogold(III) complexes induce cell death through mitochondrial ROS production

Gold compounds are being investigated as potential antitumor drugs. Some gold(III) derivatives have shown to induce cell death in solid tumors but their mechanism of action differs from that of cisplatin, since most of these compounds do not bind to DNA. We have explored cellular events triggered by...

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Detalhes bibliográficos
Main Authors: Vela, Laura, Contel, María, Palomera, Luis, Azaceta, Gemma, Marzo, Isabel
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3201811/
https://ncbi.nlm.nih.gov/pubmed/21864808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jinorgbio.2011.06.004
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